Lots of factors that determine....how high end the system is is probably not a determining factor in of itself, though better systems will probably reveal more differences in general.
Try it yourself and see. You do not have to spend a lot to experiment. Start with vanilla stock RCA ICs and basic copper zip cord speaker wire from Radio Shack. Then try a few low cost alternatives that might make a difference. I'd switch ICs first before speaker wires. Try a used pair of MIT Terminator ICs. These should cost less than $50 and the difference has a good chance of being audible. If you want to go a bit higher, try DNM reson ICs, probably less than $100 used. I'm you can search other threads here on Agon and find lots of other recommendations to consider as well if you like
Try it yourself and see. You do not have to spend a lot to experiment. Start with vanilla stock RCA ICs and basic copper zip cord speaker wire from Radio Shack. Then try a few low cost alternatives that might make a difference. I'd switch ICs first before speaker wires. Try a used pair of MIT Terminator ICs. These should cost less than $50 and the difference has a good chance of being audible. If you want to go a bit higher, try DNM reson ICs, probably less than $100 used. I'm you can search other threads here on Agon and find lots of other recommendations to consider as well if you like