Sell your Bose 301s and buy a pair of larger vintage speakers like Klipsch Hersey or Cornwall speakers. Hang, or mount them in two corners pointed towards the area you work in the most.
Bose speakers are designed to bounce sound of nearby walls creating an ambient/reverb type effect. This coupled with the long distance between multiple speakers and possibly any surround sound processing from your home theater receiver is causing all of your problems.
Bose speakers are designed to bounce sound of nearby walls creating an ambient/reverb type effect. This coupled with the long distance between multiple speakers and possibly any surround sound processing from your home theater receiver is causing all of your problems.