Help Me Choose or Confuse Me More

Hello All

I need some help. I have tried asking this elsewhere but need a group of well-rounded, more brand-agnostic opinions. 

Moved into my home office when covid hit. I needed a quick set up, because it was temporary. Now it's not temporary. So I'm upgrading some things.

I'm in the command chair about 15 hours a day. I'm on video conference meetings an average of 5 hours, the rest of the time is split between music via Tidal, or Amazon Prime TV. So I'm either paying attention to meetings, working on docs projects/sending or answering emails/approvals or projects while listening to music or background TV. 
 
Current Set Up: 2017 13" Macbook Pro > Samsung QN50Q80T > eARC Out > Certified 4k 2.0 USB-C to HDMI > Bluesound Powernode 2i > Kimber 4VS bare wire > KEF Q100s on SoundRiser Pro stands and a Rythmik F12 sub crossed at 80hz sitting in the corner. The home office was a spare bedroom at 11'2" x 9'11" with 8' ceilings. I've added moderate room treatments about 60 sq ft with some bass trap in the ceiling corners. I've gotten a bigger desk 74"W x 39"D and use a desk-sized mouse pad to help with reflections. Also hardwood floors, but I put a runner rug down with carpet pad underneath. 
I am nearfield at the desk, about 36" - 40" from tweeter, and usually the phone dB meter is between 55-65 dB.       

Upgrades Coming: Mac Mini (more ports and faster guts) and NEW SPEAKERS. I just don't know which ones.

Short List (in no order)...
Kef LS50 Meta - about $1500. I like the Q100s but know there is better. The LS50 folks love them, but is there THAT much difference from the Q100 to the LS50 Meta?  
Harbeth P3ESR - $1500-$1700 range used. The Harbeth folks love them, but historically I haven't loved standard 2 way speakers. Something about sitting distance and time alignment.
Omega CAM - about $1500. I had a pair of the Super 3i about 5 years ago and liked the sounds, but had them in my man cave system and they weren't big enough for the room. The Omega alnico guys love them, but I'm not going to use tubes for 15 hours a day.     

Even given the sub I have I wouldn't describe myself as a basshead, but some highs are very unpleasant to me. After a recent hearing test I'm out at 15KHz.

What should I get? ≤$2k and used is ok. I do not live in a part of the country where I can go listen, basically 2+ hours from anywhere.