This is one of the easiest things to test. Simply listen with everything laying on the floor. Then listen with everything propped up off the floor. Literally anything that will hold them up will do. Paper or plastic cups, pieces of wood or plastic, books, carbon fiber, string. Anything. Just try it. Trying and hearing beats guessing and spreading false information, but only by about a million times. In my opinion.
Frankly it never crossed my mind to even test this. What I did notice though is that reasonably relaxed (long enough cable, any, actually) sounds better than stretched/tight one. Never experimented with lifting the cord off the ground. It is probable that vibrations from the floor catch the cable. However they can transfer through equipment, too. So, what's best solution anyway? Dampening cable holders, I'd guess?
However the thread was about plug unplugging because of cable weight, right?