Guitar lacking bite, vocal lacking presence

Attention to setup detail as described by @mrdecibel is critical to optimizing SQ.  I would start with his recommendations.  Your speakers are known to be musical but without the extended high end of others.  Therefore, your observation on treble bite is part of the design intent compared to let’s say Magico which bites sharply.  This is not a criticism for it is personal preference.   I did not see any description of listening position.  I have found your speakers to require a listening at least 8-9 feet from the front of the speakers for the bass and treble to integrate.  That is why I never purchased them since my room requires a closer listening position.  The wooly sound quality with lack of presence may be an integration problem.  Speaker placement and room treatment are also key in achieving a balanced frequency response.  I would experiment with distance from side and back walls, toe in, rake angle.  Focusing the drivers at ear level and toward your listening position may increase presence. There is a door very close to the right speaker.  This may give bass and dynamic “suck out”.  I do not know of a better way to describe it and I awaite the comments, but as the sound wave progresses out the door it is not moved forward toward the listening position.  Is that a heater or air conditioner between the speakers?  If off, it may be a good thing acting as a defuser but when on, I am sure all level of detail is masked.  Finally, go to a good Otolaryngologist and get a hearing test if you feel your high frequency hearing has diminished.  My wife asked me to go.  The physician’s conclusion was selective hearing rather than physiological.  Good luck. 

PS. Is that a hardware store grade power strip//surge protector?   Make sure is is rated for the current draw of all equipment hooked up to it simply from a safety perspective, and this may be affecting sound quality by limiting current below demand, of slowing change in current on demand.  At a minimum replace it with an audiophile grade power strip/surge protector as soon as possible.  If possible, purchase a good power conditioner or regenerator.   I prefer conditioners.  If you are in an area where there are noisy mains, conditioners are recommended.  If in an area with frequent voltage fluctuations, regenerators are recommended. 

It's a bit confusing as I've always heard that thiels required careful setup as they tended to have a hot top end if not careful.

There is a thread entitled "Thiel Owners" which has been running forever with about 14,000 posts under the "speakers" topic.  One or two of the posters still sell Thiel speaker components and I believe are related to Jim Thiel.  There I believe you will receive additional excellent advice.  It's the place to be.

Are you sure that your tweeters are operating at full steam?

@jetter You are correct that some find the Theil aluminum dome tweeter to be “hot”.  Its frequency balance is extended up to my ears when I was considering both the 2.4 and 3.4 designs.  But, to my ears and others, there is a lack of air on top.  So, some do not like the hot Theil metal dome treble.  Others like me feel the extension that creates the feeling of air is missing.  Bottom line is something is wrong with the system or setup if there is no “bite” as posted by Andy.  

@jsalerno277 

The primary message of my post was to let @andy2 know that he would probably obtain the most on point recommendations from the "Thiel Owners" thread, here:https://forum.audiogon.com/discussions/thiel-owners-2?highlight=Thiel%2BOwners .  Dedicated Thiel owners, and people who I believe worked with Jim Thiel and still sell components (if not speakers (?)) and from occasionally visiting the thread seem very generous with their knowledge.