"Louis Pasteur's theory of germs is ridiculous fiction." (Pierre Pachet, Professor of Physiology at Toulouse , 1872)
"The abdomen, the chest, and the brain will forever be shut from the intrusion of the wise and humane surgeon," (Sir John Eric Ericksen, British surgeon, appointed Surgeon-Extraordinary to Queen Victoria 1873)
"The super computer is technologically impossible. It would take all of the water that flows over Niagara Falls to cool the heat generated by the number of vacuum tubes required." (Professor of Electrical Engineering, New York University)
"There is no likelihood man can ever tap the power of the atom." (Robert Millikan, Nobel Prize in Physics, 1923)
"Man will never reach the moon regardless of all future scientific advances." (Dr. Lee DeForest, Father of Radio & Grandfather of Television)
"Heavier-than-air flying machines are impossible!" (Lord Kelvin, president, Royal Society, 1895)
"The bomb will never go off. I speak as an expert in explosives." (Admiral William Leahy, re: US Atomic Bomb Project)
"These fuses are an insult to common sense." (@wesheadley, Denyin'tology Disciple)
When the steam locomotive came on the scene; the best (scientific) minds proclaimed, "The human body cannot survive speeds in excess of 35MPH."
Until recently (21st Century); and the advent of the relatively new science of Fluid Dynamics, the best (scientific) minds involved in Aerodynamics, could not fathom how a bumblebee stays aloft.
Often; Science has to catch up with the facts/phenomena of Nature and/or, "reality" (our universe).
I haven't been in school since the 60's, but- at Case Institute of Technology; the Physics Prof always emphasized what we were studying was, "Electrical THEORY." He strongly made a point of the fact that no one had yet actually observed electrons (how they behave on the quantum level) and that only some things can really be called, "LAWS." (ie: Ohm, Kirchoff, Faraday)
PERHAPS: that's changed in recent years and I missed it?
