Would it be fair to say (or infer) that some of these boutique fuses are somewhere along the arc between a bog standard fuse and those FNM fuses? That they are definitely a step up but still nowhere near a FNM fuse? That could be why we hear a difference: they're simply a better made fuse, kinda like what you got with the FNMs. Just saying..
Some of the boutique fuses we've seen are inferior and some are OK so there's not a good answer to this question. We've seen some that employ a Teflon tube to damp the motion of the fast blow element; this type of fuse might not blow correctly since the metal can go to liquid and still be supported by the tubing- at that point would eventually become a plasma. I'd stay away from any fuses constructed in this manner. We've seen some that don't hold the current they are rated for and some that won't blow until you're a bit over spec! None of these are good situations. Having an equipment failure on this account wouldn't be a good thing so when people ask me about this on the phone I let them know what we've seen.