They absolutely make a difference and the ones that I have had the best results with are Wireworld, especially the red starlitght 8 and my reference the Platinum (my favorite). The build quality is second to none and believe it or not (and I wasn’t a believer) they make a big difference in sound, just like interconnects. Highly recommend. Would I spend a huge amount of money? Maybe not, but these are very reasonably priced and I’m comfortable at this level for the results that I’m getting.