If you use cable risers, make sure to try them facing in both directions. The grain in the wood, plastic, Styrofoam coffee cup, and cardboard toilet paper roll interacts with the photons traveling down the cable dielectric, smearing the music. If Pat Boone sounds like he’s had one too many martinis, reverse the risers.
If you don’t use risers and your listening room has carpeted floors, at least groom the carpet fibers to lay in the direction the signal is traveling through the interconnects and speaker cables, to minimize the resistance. For the area under your power cords, install Berber carpet. The looped fibers lead to better grounding.