Dipping my toe into the high res waters

I've been using iTunes, streaming to an AirPort Express, for my computer-based music. (When I'm not playing records or CDs, in other words.) I've got close to 1,000 CDs, ripped in Apple Lossless, and quite like the ease of use -- with the Remote app on my iPod Touch -- but I want to check out this fancy new high res stuff. From what I've been reading -- and I've been doing lots of reading -- the Squeezebox Touch could let me have a foot in both worlds: iTunes and high res. I'm looking for two things: better sound, but still fairly simple. Are there reasons to avoid the Squeezebox Touch, or are there better solutions to give me a way into the high res world without leaving behind the simplicity and familiarity of iTunes altogether?
Thanks.