@raam RV's are 'tiny homes' that just happen to be mobile....*s*
We still have our 34' Safari that I'd tried various audio abstractions within....built prior to slide-outs which 'simplify' wiring but still makes 'near field listening' a given.
'Real estate' (sq. ft.) is what one doesn't have, the pre-installed audio is usually a bad joke, and the cables are basically 'zip wire'....
Go class D amps; the smaller the 'upstream' the better. Everything onto a laptop as poss..... Have the quietest genset or your batteries will not have enough for dinner or even the late snack....and morning java will require propane if you're 'dry' camping.
Forget 'room treatments'....think 'the space as oversized headphones' and you'll be less frustrated.... I never tried 'room eq' as it would be overkill and another thing to take space you don't have.
Best I could manage was a pair of ESS amt's and a pair of 6'' woofs in the kick of the driver and shotgun seat spaces....The dash player did broadcast and CD's.
You have to....No, Will give a pass from 'phile to Practical....
...unless you've a Prevost or the like. And, even then, a good pair of b/t headphones will be your biggest friend.
Good listening and luck, J