Decent moderate priced speaker for large room

Admittedly this is outside the scope of true high-end audio, but I am perplexed re: chosing a moderately priced, full-range speaker to utilize in a vacation rental house. The room is 40' x 25' w/two-story vaulted ceiling. I would like to use my PS Audio GSA-250 (250 w per ch). I know it's a tall order, but I am seeking the best combo of party level and lower listening level performance, at a price that I won't have to loose sleep over.