I have a miniDSP 2x4HD on my 4 sub array with the same amplifiers (thanks so much Duke!). As MC states, you'll be limited to one set of DSP settings per amplifier. Perhaps not ideal, but in the end you're really correcting for 1 listening position, not 4 subwoofers.
The miniDSP paired with REW and a calibrated microphone (e.g., the umik-1) is really a wonderful tool. Make the measurements at the listening position and immediately import directly into miniDSP to create the appropriate filter. *Many* more options and flexibility than the onboard EQ settings on the Dayton, and if you're set up correctly, you can make all the changes directly from your listening position. I find that invaluable for evaluation accuracy. So much easier than getting up, moving a tiny knob without feedback, and then sitting back down and trying to figure out how the sound changed.
The miniDSP paired with REW and a calibrated microphone (e.g., the umik-1) is really a wonderful tool. Make the measurements at the listening position and immediately import directly into miniDSP to create the appropriate filter. *Many* more options and flexibility than the onboard EQ settings on the Dayton, and if you're set up correctly, you can make all the changes directly from your listening position. I find that invaluable for evaluation accuracy. So much easier than getting up, moving a tiny knob without feedback, and then sitting back down and trying to figure out how the sound changed.