Best small, desktop speakers, $500 or under (new or used)

Google "Arche Audio FR2" speakers ($300 delivered) and you will find positive online reviews.

DeKay

I have both Vanatoo Zeros and One Encores.  Excellent self powered speakers with built in DACs.  The One Encores work on a desk or stands.  The Zeros are especially good for Desks.  Very adjustable and sound excellent when you turn off the compressors that are on when sent out from the factory to keep people from overloading them with bass heavy music at a dance party.  Easy to turn off.  I met the company owners at Florida Audio Expo a year ago and their demo was pretty amazing for the price of this product.  Highly recommended for your desk!

@b_limo 

Just wondering, have you heard the Max paired in stereo mode? You'll be surprised.

My reference to the LS50W with regards to its pricing/value. If the Max didn't exist at its price point then there is no argument.

Lots more good suggestions. No one has tried the Ascend speakers? Hmmm.

One thing is certain — I really am hoping for a real speaker, not just a "computer speaker." It seems that's possible, but there are a number of computer speakers thrown into the mix here, so I'm not sure where the line is for people between "real" and "computer." Perhaps that's too subjective to even wonder about.

The Peachtree interest me -- however, I do I have a (somewhat older, but still $500 new) peachtree DAC.

As much as the Totem Rainmakers appeal, I did find that 14" height is just a bit big for 2-3 ft. nearfield.

The pressure is mounting for the Vanatoos; might be coming in for a serious look.

Zdac, 
I have heard the LS50w’s properly set-up and they are downright amazing.  They compete with many of the dozens of high end speakers I have owned.  I’ve owned LS50w’s.

I have never once heard, or heard about the speakers that you mentioned.  I find it strange though that you only have 2 posts... do you work for the company or you are just a satisfied customer wanting to share your experience? I will look into them a bit more.  I do hate when someone makes remarks about something they haven’t heard, and thrn I go and do it 🤷🏼