Best Loudspeakers for Rich Timbre?

Lively room for sure, you can tame and tune it.

I don't understand the science of it but why do I feel that Duke is right ? I listen within 10 feet, I guess it's almost nearfield.

Now we are getting somewhere - boxes, panels, horns..

- Compensation is necessary to create the illusion of recreating the original -

Exactly, and well-said.

terry9, Purist Audio's designer is a former NASA engineer specializing in underwater acoustics and signal transmission. Tchernov cables are designed by engineers building military grade equipment. I am sure those people understand enough of physics. But Jim Aud of Purist is also clearly an artist with excellent hearing. If you think that you can compete with them and others, that's okay with me but that's not a proof.

Spending $10 on cables would get anyone nowhere, unless you steal these cables and $10 is your taxi bill. 
It is remarkable that many don't understand that cables are components, they are equally important. Another mistake is to think that they are easier to design than electronics, speaking of high level.
How to best stretch your dollar when upgrading cannot be answered in general, sometimes it should be active component upgrade, sometimes cables or power cords, and yet at times either would be a correct path, just different.

I don't have a specific recommendation but I do think that the OP wants very high performance level. And the rest of the system, including recordings, should be up to this as well. $50k set-up for a medium size room ? At least.