Ok. If I am running interconnects for several hundred feet… it is important. But this is a condition that is vertically nonexistent in high end audio.
The reality is that the quality of the interconnect usually trumps single ended versus balanced for the vast majority of actual systems. I have never heard a system where the single ended / balanced was a significant factor. The additional cost for balanced typically is significant. So, it really remains best a dilemma for folks with very high end systems. If you have to be budget conscious. Then get single ended… don’t think twice. If you are trying to assault the highest achievable… then try both.
My average component cost is $20K and my manufacturer recommends balanced… I couldn’t detect the difference… so it is small. I suggest worrying about the big stuff… this ain’t it for most folks.