If one of the generally accepted benefits of long runs of balanced interconnects between a preamp and an amp is noise rejection, is this still true whether or not the amp in question is a differential unit?Yes, provided that the driver and receiver circuits that interface with the cable are balanced (which is usually but not always the case if XLR connectors are provided), and of course as long as the cable is balanced. A balanced pair of signals do not necessarily have to be provided, but the impedances in the two interface circuits between each of the two signal lines and ground have to be equal (or close to it), for the noise rejection benefit of a balanced connection to occur.
Also, regarding balanced vs. unbalanced connections when the components do not have internally balanced or differential signal paths, see my post here.
Best regards,
-- Al