No, the room size will not be a problem (my room is about the same size). But the amps won't cut it, I'm afraid. You need more power than 160 W/side. I run my N802s with VTL 450s and I need every last drop of power.
The N802s are very power hungry, they come alive at only louder listening levels, and a larger room also demands more power.
The N802s are very power hungry, they come alive at only louder listening levels, and a larger room also demands more power.