Audio Note Neiro PSE schematic with 45 tube versus Wavac ES-300 IITC schematic


I am thinking to get a custom built amplifier, and considering the following:

Audio Note Neiro Parallel Single Ended with 45 tube (instead of 2A3)
Wavac ES-300B IITC 

I am wondering if anyone have some input on either one of schematic, or can predict what are the differences between the two.  I searched on the internet, but can't get much reviews or opinions for both of them.  It seems the Neiro would be fun.  It has 2 x 45 tube in parallel to give more power, and I hope it doesn't lose the characteristics of 45 tubes.  And if I don't need that much power, I can just use one pair instead of two, it seems.

For the Wavac, it seems the IITC circuit is special, maybe that's why it got mixed reviews.  Some likes it and some don't.    
gte357s
Paralleling two 45's will give 3.5 watts (in theory). Equivalent to a single 2A3. I have both a SET 45 (Will Vincent) and a SET 2A3 (Sanei 560). Either output tube makes beautiful music! Problem is finding a good speaker match! I'd go for the AN Neiro! General consensus seems to be that either the 45 or 2A3 are preferable over the 300B!
In single ended, i would not use two tubes in push pull config or parallel.  I recommend using single 45 or 2a3.   If wattage is a must then use a single 2a3.   If you have speakers that are efficient then a single 45 would be a better choice.  
@roberjerman Thanks for the reply. Actually, I am using a (in my opinion) very good 2A3 by Triode Lab from Canada.  Since the 45 PSE also output ~4W, do you think it will sound too similar to my current 2A3, or it really depends on the schematic?
@zipost Please educate me, what is (in theory) the effect of having two tubes in parallel?  I know that it will give more power so I can play the music louder to fill a bigger room.  But I don’t need louder.  For my current 2A3, the volume knob is at about 9 o’clock.  So, I predict even for a single 45 tube at 2 W, maybe my volume knob will be at 12 o’clock?  But with two tubes in parallel, will it make any tonal difference such as having more “weight” or bass?

@zipost Please educate me, what is (in theory) the effect of having two tubes in parallel?  I know that it will give more power so I can play the music louder to fill a bigger room.  But I don’t need louder.  


Different designers has different theory.  It’s depends on what you are trying to accomplish as a user.  Parallel usually will give you more bass control and louder on volume.  


For my current 2A3, the volume knob is at about 9 o’clock.  So, I predict even for a single 45 tube at 2 W, maybe my volume knob will be at 12 o’clock?  


I can’t really answer this questions, due to the nature of your preamp ( type of preamp, db gain and how it was built).  I usually like my volume at 12 o’clock and max at 3 o’clock.  That is just me, what works for me might not work on your systems.  


But with two tubes in parallel, will it make any tonal difference such as having more “weight” or bass?


single ended and parallel single ended to me are both different approaches.  Usually two tubes parallel will give you more bass control on the woofer, increase in volume and more dynamics.   If you are running single ended amps ( 45 or 2a3 tubes) I assume that you have pretty efficient speakers 100+db.   A Single 45 will for sure gives you more magic, mesmerizing vocal and organic sounding.  All of this factors in what kind of music you listen too and room sizes.  If my speakers are efficient enough, i would stick with single tube, single ended designs.