Great topic. I too agree it can take a long time to really appreciate & understand what a certain component is doing or how it sounds. Often, once you get used to that new sound, it becomes our new standard & how we think it "should"sound. It's a strange phenomena.
That said, comparing speakers in the same system doesn't take very long & to me, usually sound quite different. This can be due to the amp driving them or the room & set up & the synergy between it all & the speakers so it too is not a for certain thing what is creating the differences, but they are usually very clear.