Feel like I'm outta my mind....

Some suggestions above involve big dough.  So listen widely and think long and carefully.  So many here have said they bought an item and then changed it a short time afterwards.  As you're getting on in years (like me), I suggest viewing these changes as your 'forever system'.

Consider the size of your listening space before buying speakers.  Some need more breathing space than others.

If you’re going with dual subs (I think you should, as they eliminate any lumpy inconsistent base response throughout a room, unless it’s the size of an auditorium) then I suggest using high sensitivity speakers.

Dual subs generally eliminates the need for low lower sensitivity speakers, which dig deeper in bass response .

IME using high sensitivity mains and dual subs (properly crossed over) unloads the mains and allows you to enjoy much better effortlessness in sound, resulting in much cleaner and dynamic sound!

Hi,  I've had a lifetime's worth of speakers - more recently Sonus Faber, Quad, Canton, Magico (S1 2), Ktema, Monitor Audio Gold 300, etc. Fed up with them all in no time: the small Magico 'bite' and edginess, much the same for the MA 300s (no bass), while the Cantons 3Ks were simply boring and the Quads didn't like the humidity here. Of course, much of this has to do with system matching, but both myself and a now retired hifi dealer that I am great friends with have tried a huge array of gear. And not coincidentally, we have both ended up with speakers from far-off Lithuania:  AudioSolutions - the Figaro Ls in my case. No, they're not American or British, and they're not made in China; but they really 'dance'. Great tonality, sweet mid range, tremendous bass and as good a soundstage as the rest of the system allows. No, they're not world-beaters, but they are great for everything from Tool to Tord Gustavsen and Alice Sara Ott, and don't cost two arms and three legs. Put that down to a combination of old-fashioned, but also traditional, paper cones and very complex (and very dense) cabinet design. They are heavy and need a bit of room to breathe, but are a rare find in a world of insane hifi prices. Next step up would be Magico S5s, but I'm damned if I'm going to pay more than three times what I paid for my Figaros for a fractional gain. For what it's worth.     

Wow! This might be the best discussion I’ve ever been a part of! What a great bunch of folk here! I feel like I’m really, really, really outta my league, but the google searches are a pile of fun!

I really like Johnny’s comments about sensitivity - that’s what I’m looking for most - effortless sound; let the subs do.....’sub things’, and let the speakers do what they’re meant to..... The room is a weird one; might require some tweaking, but it's been pretty great so far.......