With high powered tube amps, I don't think there are many restrictions on what speakers can be used with the amp. The issue with low impedance speakers has to do with the interaction between the amp output impedance and the impedance of the speaker affecting the frequency response. It is NOT a safety issue because tube amps can safely run into very low impedances (even a dead short). If a 4 ohm rated speaker remained at 4 ohms across the entire frequency band, there would be no change in the frequency response resulting from the output impedance of the amp. But that is never the case, and the closer the output impedance of the amp is to the impedance of the speaker, the greater the interaction with respect to frequency response. Tube amps tend to have a higher output impedance than solid state amps meaning that there is more of a tendency to affect the frequency response. While it is generally better to avoid such interactions and the attendant frequency response changes, sometimes these changes can actually sound good. Hence, higher and flatter impedance curve speakers tend to be better for use with most tube amps.
For my personal taste, I generally tend to like low-powered tube amps over high-powered tube amps. There are many high-powered tube amps that sound lean and brittle (hard) to my ears such that if I really required a lot of power, I would go with solid state (the sin of most solid state amps is that they sound dead and unengaging at low volume levels, but this is better than being hard). Hence, tube friendly, to me, means a speaker is both reasonably efficient and has a reasonably high impedance.
I have not heard your McIntosh amp and I am not familiar with the sound of EL509 tubes, so I can only offer very general advice. If you know the output impedance of your amp, that might help you decide whether it matters at all if a speaker is "tube friendly." It the impedance is under one ohm (equivalent to a damping factor of 8), it can probably work well with just about any speaker on the market. If it has a damping factor above 8, there is even less restrictions. Below 8, you may have meaningful frequency response swings with lower impedance speakers, such as those rated at 4 ohms.