I'm currently running a D-Sonic that is a 7channel setup w/ both front speakers bi-amped and couldn't be happier. As far as config, you can go with whatever you specify and remember, even in a 7 channel chassis, each amp is discrete as would be a mono.
In my system, my speakers are hard to drive and go down to 2.7ohm so I'm running 2KW (4ohm) to each speaker (nautilus 800) and compared to lower-powered A/B amps I used previously the D-Sonic takes absolute control and drives these things as they were intended.
As for AC noise/ power, you obviously know already that class D amps inherently resolve that issue and this amp is 100% dead silent. Once you get used to the fact that class D is a nonlinear pulse wave modulated architecture with incomparable immediacy (compared to class A or A/B) I think that you will be pleased.
If you end up going the D-Sonic route, my recommendation is to get the highest output modules that fit within your budget now so you can be sure that you never outgrow the amp if you ever decide to change out your speakers.
Let us know what you end up doing.
Take care
Greg