I had my Maggies 3.6 bi-wired with Nordost Red Dawn Rev II prior to getting the Remote Sense. The Remote Sense brings much more clarity and control to the sound. This cable sounds as if there is no cable between the amp and the speakers.
The Musician III SE allows you to run the Remote Sense with another cable as a bi-wire configuration. For instance, the Remote Sense can be connected to the mid-range and tweeter, and another cable can go to the bass driver. I tried this configuration with the Red Dawns. The problem was that the Nordost cable is bi-wire and I could only connect two of its four connectors. So I think I was missing some of the signal. In any case, the character (or lack of character) of the Remote Sense didn't allow for a good match between cables. That's something to take into account if running the Remote Sense with another cable. The other cable must be fast, taught and clean.
I ended up just using the Remote Sense for as long as I had one amp. I now have two M3 SE in mono-block configuration and the Remote Sense cannot be used in this setup. So I had to let go of this great cable.