Geek, I've heard earlier versions of the Model 2 in rooms larger than yours sound just wonderful. In fact, due to the physical design of Vandersteen speakers, I believe they benefit from placement further away from both rear and side walls than most other speakers.
The Vandys with built in powered subs can be better than most other speakers due to the fine tuning for the room which can be achieved. Still, I expect one advantage with either the 2 or 3 is the ability to place them for optimum performance within the room, then locate the Vandy subs separately for their best performance. Optimum mid-range spaciousness and openness will not necessarily be the best location for smoothest bass response.
The Vandys with built in powered subs can be better than most other speakers due to the fine tuning for the room which can be achieved. Still, I expect one advantage with either the 2 or 3 is the ability to place them for optimum performance within the room, then locate the Vandy subs separately for their best performance. Optimum mid-range spaciousness and openness will not necessarily be the best location for smoothest bass response.