Done all the time. Put the cable with best highs on the hF posts. Other cable on the LF posts. I have done this with many brands of cables with good results.
Two different cable pairs from amp into speakers
I have two different bi-wire cables with different strengths. One cable excells in the treble and mid-range and the other excells in the bass department. One cable is spade to spade and the other has bananas on both. My question is: Can I hook up both sets from my amp to my speakers (Piggy Back)? I want to use both biwire ends into the speaker and not let one bi-wire end hang loose. Will I get the best of both cables by combining the two or will the two different cables smear the sound? Maybe I should have each separate cable go to the different terminals on the speaker and not combine the cables? Thanks.