Totem Mani 2 sig vs Dynaudio special 25s

In my experience, the Focus 140's and the Special 25's are very different sounding -- there's hardly a family resemblance to speak of.

I have owned two different models of Harbeth as well as the Focus 140 and Confidence C1. People used to talk about some speakers transporting you to the recording venue and others bringing the musicians into your listening room. Harbeths are very much in the latter camp. Their midrange is rich, ripe, seductive and convincing, especially on vocals. The tradeoff is that they they are low resolution (others will argue with this I'm sure) -- you do not get much information about the recording venue, nor do you get much detail or spatial information in general. And Harbeths are not transparent to the source, meaning you will hear less difference between components ahead of them in your system (amps, cables, sources). This can be both a blessing and a curse.

At the opposite end of the spectrum lie ultra high resolution speakers. Most electrostatics, which tend to be very transparent to what precedes them. Likewise Thiels. (I have owned and loved both). I imagine the Berrylium tweeter speakers fall in this camp as well. When I had the Focus 140's, I felt that they shared some of the overall warmth of the Harbeths but also excelled at spatial information. The Confidence C1 (and I think the Special 25 also) are more neutral. The Special 25 may be more to the high rez side of the scale, while the C1 falls nicely in the middle, to my ears.

I hope this is useful. You really can't go wrong with any of these choices, but personal preference is the key variable and only you can weigh in on that.