Price no object: Heard the MBL Radialstrahler 111E at the HK Hi-Fi show last year and they are definitely the best I've heard. They need a big room and an even bigger wallet though.
Keeping feet on the ground (barely): ATC SCM100 (Active). Possibly the best midrange I've ever heard.
Keeping feet on the ground (barely): ATC SCM100 (Active). Possibly the best midrange I've ever heard.