Glai points out that using DRC to address a null can be difficult, but it can be done. For example, several manufacturers produce a 12" sub with 1000 WPC. A pair of such subs (especially those with largeish cabinets) will provide 2 kW of amplifier power (more on peak) into a reasonably sensitive driver/box mechanical system, which will go a long way toward fixing the most stubborn null. This is a blunt force approach, maybe inelegant to some, but it works. As Glai notes, it may also prove expensive.
Good Luck
Marty
PS - When I note that your 40hz null will be mostly inaudible, I assume that it's deep and narrow @ 40hz. A broader null (particularly one extending higher in frequency) might certainly pose a more audible problem.