As the record revolves, the stylus naturally wants to skate toward the center of the record, and anti-skate is meant to keep this from happening. So do your best to get the amount of anti-skate as dead-on as possible.
My method of achieving this is to put my least-warped LP onto the turntable and placing a nice, tiny spirit level on top of it. Once the LP/platter combo is leveled, home in on the proper amount of anti-skate force by adjusting anti-skate force a little bit at a time until, when you lower the needle into the moving groove, the tonearm-cartridge duo doesn't want to shift either forwards or backwards when it touches down..
I got to say, too, that LP edge-warp is one of the banes of the analogue universe.