In my case it worked!
I had a problem with bass response in my old living room with low ceilings, 7’8” with hard “plastered ceilings”.
Had dual (stereo) subs at the time, with lots of bass traps. My impression (and others) was while standing and/or mulling around listening, the bass response was nice and tight (punchy). But once you sat down, that sensation was gone. We presumed it was a standing wave problem, due to the shortest (and usually most offending) dimension of the room (floor to ceiling)
We tried setting subwoofers at mid height which did help, but it wasn’t until we set up a single bass array (sort of a stacked sub or array approach) that it eliminated the problem.
Most folks aren’t willing to do what it takes with multiple subs due to finances, aesthetics or both, so they compromise (live with bass nulls and or just sit (or stand!) in the best spot).
For me It’s redundant and obvious to say that if your insisting on uniform and even bass response throughout your room, then the subwoofers orientation must slave to its dimensions.