We had this issue with my mother-in-law several years ago. While I don't have a particular model to recommend, I will say that it is very important to pay attention to finding one that makes changing the settings fairly difficult, or else you will run the risk of the user inadvertently reprogramming it out of frustration, if she can't get it to work as desired.
Special Remote Control Need
My friend's mother is in an assisted care living facility and has arthritis & vision problems, as well as many other medical problems. He is trying to find a VERY SIMPLE universal TV remote control (on/off, channel up/down, volume up/down). The fewer and bigger the buttons, the better!!! Thanks for any help, folks!