That's a big room to fill. I used to own Spica Angelus and the Green Mountain Audio Europas are better in every way, including imaging. However they would struggle to fill such a large room without a subwoofer.
I think you may struggle to fill a room that size with music AND have the subtlety and imaging of the Spicas on the stated budget. The Europas might do it if you budget for a good sub in the future (I use a Rel strata).
You could fill that room with music with B&W DM603s, but you'll lose some of the refinement of the spicas. The B&ws are a lot of fun, though.
I think you may struggle to fill a room that size with music AND have the subtlety and imaging of the Spicas on the stated budget. The Europas might do it if you budget for a good sub in the future (I use a Rel strata).
You could fill that room with music with B&W DM603s, but you'll lose some of the refinement of the spicas. The B&ws are a lot of fun, though.