Roon is pretty well unrivaled in terms of options, interface, and usability. It is, however, a very heavy software. Roon prioritizes features and end user experience over sound quality (although it has improved over time).
There is a tremendous amount of network activity occurring within Roon. High amounts of network activity can contribute to the "harsh" sound often attributed to digital audio. Minimizing network activity within the server can net positive gains. I believe this is a major reason why alternatives such as Sense, Lightning DS, and Stylus are reported to sound better. Taiko set out to mitigate the impact of network activity on sound quality in their proprietary TAS software. This was a major focal point for them, and many SGM Extreme users report that streaming from Qobuz/Tidal now sounds indistinguishable from playing local files.