I think you gotta live with it in the system for a while. You might hear a difference with a quick A - B comparison but it would be very logical for that to be affected by your expectation that you will hear a difference, just like @jasonbourne71 mentioned, and seeking/paying attention for what stands out. That can be very subjective and in my experience results might switch on you.
In my experience there’s little doubt that the interconnects can make a big difference, but whether it is an improvement or just a change in the frequency response in some part of the range can be a challenge to determine.
@jasonbourne71 I have a question for you - not trying to start an argument - have you ever tried swapping any wires in your system? I’m curious what you’re using and how you arrived at your setup. I was a cable agnostic until an unexpected encounter plainly demonstrated a difference between my standard interconnects and another pair. I was irritated to find that power cords made a difference, a power conditioner made a difference, interconnects and speaker wires. I am glad I had this experience, as my system sounds much better than it ever did before. I kind of kick myself that I spent so many years listening to wires that were negatively impacting the sound of my system.