You are referring to digital volume control. If the volume is controlled in the digital domain, it is controlled by stripping bits, so effectively you are reducing the resolution. The further you get from 100% volume, the more bits are stripped to create the reduced volume. So, 100% volume contains bit perfect signal. Anything less than 100% volume loses some bits and the future you get away from 100%, the more bits and resolution are lost.
This is my rudimentary understanding of the potential issue.
Are you connecting the analog outputs from your Oppo directly to a power amp? No pre-amp for volume control? And are you using the digital volume control built-into the Oppo to control the volume?