Rrolack,
FWIW,
I use exactly the type of set-up you're describing. A tubed ARC preamp (LS 25) feeds an NHT X-2 active x-over. The NHT high pass out (signals over 75hz) feeds an ARC VT 130SE. The main speakers are usually Ohms, but I also ocassionally rotate in Maggie or Verity speakers.
The low pass out of the X-2 feeds a Velodyne SMS-1 subcontroller which allows for digital room correction and fine tuning of the high cut filter characteristics for the sub's top end roll-off. This signal, in turn, feeds 2 Rythmik 12" subwoofers.
The results have been enormously satisfying in a very tough room and the NHT X-2 has little to no (to my ear, anyway) impact on the main signal path.
As always, YMMV.
Good Luck
Mary