One of my setups uses a JC 2 BP and JC 1 monoblocks to drive KEF Reference 107/2s, another uses an Ayre K-5exMP and VX-5 Twenty KEF to drive KEF LS50s. Though the speakers are obviously very different, my general observation is that the Ayre based setup sounds a bit warmer, whatever the acoustic correlates of warmer are. Someday, I expect to try the Ayre stuff with the big KEFs, and hope to have replaced my K-5xeMP with a KX-5 Twenty to match the amp.
The Parasound setup uses an Esoteric SA-60 disc player, the Ayre setup an Ayre C-5xeMP.