This will depend a lot on the your speakers. How efficient are they?
Depending on the speakers, high gain might mean that you are only able to use a small fraction of the range of your volume control (which would be the case if your speakers are very efficient). On the other hand, low gain might mean you are not able to get your system to play as loud as you want (if your speakers are not very efficient).
Depending on the speakers, high gain might mean that you are only able to use a small fraction of the range of your volume control (which would be the case if your speakers are very efficient). On the other hand, low gain might mean you are not able to get your system to play as loud as you want (if your speakers are not very efficient).