My second room (bedroom) is about that size, maybe a tad smaller on the long side. I'm using Triangle Titus ES on 24-inch stands about 21 inches from the short wall and a bit more from the side walls. Listening is near field, of course; I sit on the bed.
It's not ideal, but I've been putting a bit more attention into it since the living room acquired a TV. I'm optimistic that with some room treatment the Tituses will produce the image and extension I heard them do in the store; already the setup is working quite well. There is quite acceptable bass from the tiny midwoofer--an advantage of the small room.