What ever is your preference is the way to go. I lean toward musicality as long as the timber of instruments sounds correct to my ear. I have been unable to get them all to sound right in a modest system so I concetrate on the ones that are more important to me such as piano, strings, voice (both M & F), cymbals and light percussives. I have not been able to get larger drums to do the trick and brass is just OK. It is all a matter (for me) of taste, balance, budget and how far I am willing to go in regard to room acoustics (noy very far other than speaker placement). I do not enjoy listening to microscopic flaws in my source material and prefer that they remain hidden.
musicality vs. accuracy
I am trying out interconnects and some sound very accurate AQ Annaconda, Nirvana SX. Some sound less accurate but to me more muscal HT, Acoustic Zen, Cardas. Which is better? When I listen to the Audioquest There is less between the images but it doesn't seem as thrilling. It kind of reminds me of the reivew of the Wisdom loudspeakers in TAS by harry pearson. He said at first the speakers sounded accurate but not very involving but after trying a dozen Amp, preamp combinations he settled on the Gamut power amp and the speakers ended up being very fun to listen to.