Yes, read the thread linked by Elliot. Lots of valuable info.
I strongly recommend you remove the arm tube in order to install the cartridge. Much less likely to damage the cartridge. Setting azimuth is quite simple. Simply loosen the screw at the rear and top of the arm tube and rotate as needed. Of course retighten when done.
VERY IMPORTANT: a cartridge with a different weight and height is likely to throw the balance of the arm off. It is unlikely that whatever surface your table sits on, or the table itself is perfectly flat. There is no typical anti-skate adjustment to correct for a tonearm’s tendency to want to move towards the inside of an LP, or towards the outside of the LP. Either tendency will cause the stylus to favor one side of the groove or the other. There is an adjustment screw in either side of the bottom of the pillar that holds the manifold housing that can be turned with an Allen wrench that allows this adjustment and balance the movement of the arm. Put the stylus guard on the mounted cartridge and using either cueing method gently cause the arm to “bounce” a bit on the bearing tube and observe the movement of the arm. Does it want to move inwards or outwards? Make necessary adjustment if needed.
I highly recommend you read the ET2 manual for detailed instructions on all of the above and much more: Good luck and enjoy this great arm: