You rebuilt the power supply? Did you replace the filter caps and resistors to bias the unit correctly. Loosing a valve is easy to check. Swap left to right on the power tubes after giving them a GOOD visual. Same with the small valves, swap left to right.
3-5000 hours on power valves, 7-10,000 for the small valves. BUT valves do fail.. No matter who makes the gear.. No matter who makes the valves.
Regards