Tony, it depends on the output impedance of the source. You will have roll-off issues only with high impedance output drivers.
There are other issues with long wires, which have mainly to do with noise pickup, as you know... The noise issues are much less severe with speaker cables. That is because noise in interconnects gets amplified and noise in speaker cables just loads the speakers, possibly interacting with the amp, but in general it does not get amplified by the electronics.
Short interconnects rarely need shielding for noise/hum reduction. Long ones rarely get away without proper shielding. So, lots of reasons to go with a "traditional" short IC/long SC.
BTW 12-16 pF/ft is not typical. Check specs more carefuly!
There are other issues with long wires, which have mainly to do with noise pickup, as you know... The noise issues are much less severe with speaker cables. That is because noise in interconnects gets amplified and noise in speaker cables just loads the speakers, possibly interacting with the amp, but in general it does not get amplified by the electronics.
Short interconnects rarely need shielding for noise/hum reduction. Long ones rarely get away without proper shielding. So, lots of reasons to go with a "traditional" short IC/long SC.
BTW 12-16 pF/ft is not typical. Check specs more carefuly!