The worst offender causing the ailment of "Listening Fatigue" is the acoustic suspension speaker as designed by Kloss and Allison in the early 1960's and still around today. The scientific reason the resultant sound completely wears me out in less than ten minutes is due to the nature of the acoustic suspension enclosure (completely sealed) that sucks the energy of the amp resulting in 10DB or more loss of acoustic watt db's. The sound is so unatural that the listeners brain MUST then make up for the loss of "Reality" in the produced sound, this overworks the brain during the first few minutes of listening. This overtaxes the acoustic center of the brain (Temporal lobe).The sealed acoustic suspension speaker enclosure is the single WORST audio invention of all time.Although benifiting amp manufactoures who then made 200 watt amps. On the other hand EFFICIENT enclosures (horn and reflex) do the exact opposite and energize my brain. The acoustic suspension enclosure sucks acoustic energy and brain energy(and more dollars for hi watt amps).