I have not heard Harbeths, but I have had a pair of LS50s for a few years and have used them in a similar setup on my desk. I agree that they will sound better on stands, but I still enjoyed them on my desk. The great thing about the LS50s is that they will fit whatever space you have (generally). I have used them as nearfield monitors on my desk and on stands in larger rooms and they perform well in either scenario.
I just came across a post on Reddit a few days ago with an impressive setup with a pair of LS50s and a small sub in a large room
http://i.imgur.com/sFJ5BUr.jpgI have also seen them in a setup much like what you’re describing and generally used with a pair of IsoAcoustics stands
https://i.redd.it/jhhyw0xpbxj01.jpgI would think these show how versatile the LS50s can be.