this is one of those "all things being equal" situations. where yes, more power is always better if the amps are otherwise equal. the reason for that is that amps sound better when they have headroom, meaning they are operating in their lowest stress point and lowest distortion point, which allows them to give the music ease and authority.
OTOH it’s rare that all things are, in fact, equal, between two different amps. some less powerful amps have simpler, more musical and refined sound than more powerful amps do for various reasons. so even though an amp might have an easier time with some speakers in some rooms, you cannot paint with a broad brush since amps circuits vary.
there are some obvious amp <-> speaker pairings in large rooms that are not going to work very well. so sometimes you really do need that more powerful amp. but your goal should be the right amp, not necessarily the most powerful.
one other important factor regarding amplifier and speaker matching for a particular room is the type of music you want to hear. if you want 'large scale' and 'very dynamic, complex' music to sound natural and not limited then more power is more significant. if you like small combo or girl with guitar mostly then amp headroom is not as important. if then later your tastes change then the system capabilities might need to change with it and you may need a more powerful amp, or an easier to drive speaker system.