It's up to you. The least that could happen is that you will get some crud on the stylus (just clean it off) and the worst is that their will be "hard" particles in/on the LP that will damage it, however slightly, when played.
New and seemingly unplayed LP's are usually very noisy when played without a cleaning from my experience (there is some kind of white/light powder in the grooves and on the surface).
Maybe try a good "hand held" wet brush and a dry carbon fiber brush if you don't feel like using the machine (this is easy to do while the LP is spinning on the table)? I do this often when I get home and want to listen to a new purchase that looks fairly clean (no boogers and such:-). I zap it with a Zero/Stat, run the dry brush, run the wet brush and end again with a clean dry brush (30 seconds tops).
New and seemingly unplayed LP's are usually very noisy when played without a cleaning from my experience (there is some kind of white/light powder in the grooves and on the surface).
Maybe try a good "hand held" wet brush and a dry carbon fiber brush if you don't feel like using the machine (this is easy to do while the LP is spinning on the table)? I do this often when I get home and want to listen to a new purchase that looks fairly clean (no boogers and such:-). I zap it with a Zero/Stat, run the dry brush, run the wet brush and end again with a clean dry brush (30 seconds tops).