After you add the mscaler/Dave, then measure the speakers & subs and use these impulse responses to set delay. DEQX will measure what it hears from the speakers, irrespective of what is in between it/them.
Because I don't have details of your specific speaker wiring your previous posts infer that there are two sets of cables to each speaker - one for mid/high and another for the 'subs' (ie woofers - your post says ...."in my case I will need "single amp with stereo subwoofer" as I have two subs - they're built into my speakers")
If you set P1 with the subs disabled, then bass frequencies may not be present as the cabling feeding the subs will not have a signal. It all depends on the frequency range of your speakers without the 'subs'.
Because I don't have details of your specific speaker wiring your previous posts infer that there are two sets of cables to each speaker - one for mid/high and another for the 'subs' (ie woofers - your post says ...."in my case I will need "single amp with stereo subwoofer" as I have two subs - they're built into my speakers")
If you set P1 with the subs disabled, then bass frequencies may not be present as the cabling feeding the subs will not have a signal. It all depends on the frequency range of your speakers without the 'subs'.