If I were to start all over again for whatever reason, and a flood or fire would be a good enough one, I'd get pretty minimalistic. A great DAC... very nice integrated... and great speakers... this time probably monitors and subs.
What Tpreaves posted is all correct too... getting out and previewing some new stuff in a nice venue where the setup is likely to be pretty good is where I'd begin.
In my choices, I'd lean towards having tubes in the int at least as I find tube sound on avg. better than SS. it might be the other way 'round for you.
You also might want to completely forgoe the DAC route and jump dead into wax with a super TT and so forth. A very good int allows for wxpansion or growth... and a nice spot to start from... or wind up with for that matter.